End-stage renal disease is also known as end-stage kidney disease and it occurs during a chronic kidney disease where the loss of kidney function reaches an advanced state.

In this stage, kidneys are unable to meet your body’s needs as they fail to work.

Symptoms

There might be no symptoms in the early stages of chronic kidney disease. But as it progresses the symptoms include:

· Vomiting

· Nausea

· Fatigue and weakness

· Change in your urination

· Sleep troubles

· Reduce in mental sharpness

· Swelling in feet and ankles

· Muscles twitches and cramps

· If fluids build up in the lungs, then it may lead to shortness of breath.

· If fluids build up in the lining of the heart, then you may experience chest pain.

· A high blood pressure which is difficult to control

· Constant itching

Causes

When a disease or a condition impairs kidney function then kidney disease occurs which damages the kidney or worsens it over months and even years.

Here is the list of diseases that can cause kidney disease.

1. High blood pressure

2. Type 1 or type 2 diabetes

3. Polycystic kidney disease

4. Glomerulonephritis which is an inflammation of the kidney’s filtering units.

5. Pyelonephritis which is a recurrent kidney infection.

6. Interstitial nephritis which is an inflammation caused in the kidney’s tubules and surrounding structures.

7. Vesicoureteral reflux is a condition that causes the urine to back up in the kidneys.

Other risk factors are as follows:

· Diabetes with poor control on blood sugar

· After a kidney transplant, a kidney can occur which can cause end-stage renal disease.

· Older age

· Lower level of kidney function

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