Moyamoya disease is a rare and progressive cerebrovascular illness caused by blocked arteries in the basal ganglia at the base of the brain.

Blood flow to the brain is reduced as a result of this. In an attempt to supply the brain with blood, tiny blood veins grow near the base of the brain. A ministroke (transient ischemic attack), stroke, or brain hemorrhage may occur as a result of this illness. It can also impair your brain’s function, resulting in cognitive and developmental delays or disability.

The name “moyamoya” comes from the Japanese word “moyamoya,” which depicts the tangle of tiny vessels that emerged to compensate for the blockage.

Moyamoya illness was initially identified in Japan and is now prevalent in people all over the world; it is more common in Asia than in Europe or North America. Children are the most commonly affected, however, adults can also be affected.


The actual cause of moyamoya disease has yet to be discovered. The higher occurrence in some Asian countries, according to researchers, strongly supports a genetic factor in some populations. Down syndrome, sickle cell anemia, neurofibromatosis type 1 and hyperthyroidism are among the disorders linked to Moyamoya syndrome.

However the cause of moyamoya disease is unknown, some variables, such as Asian ancestry, family history, and history of moyamoya disease, may raise your risk of developing the disease.

Females have a somewhat higher frequency of moyamoya illness, according to research. Another risk factor is that the disease mostly affects young people and is most frequent in children under the age of 15.

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